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LEAPChem Highlights Gentamicin sulfate (1405-41-0)!

Nov. 2018/4/24 15:22:04 By LEAP Chem


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Basic Information of Gentamicin sulfate

Chemical Name: Gentamicin sulfate

Cas No.: 1405-41-0

Molecular Formula: C21H43N5O7

Chemical Structure:

 1405-41-0.png

 

Gentamicin, sold under brand names Garamycin among others, is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not effective for gonorrhea or chlamydia infections. It can be given intravenously, by injection into a muscle, or topically. Topical formulations may be used in burns or for infections of the outside of the eye. In the developed world it is often only used for two days until bacterial cultures determine what antibiotics the infection is sensitive to. The dose required should be monitored by blood testing.

Gentamicin can cause inner ear problems and kidney problems. The inner ear problems can include problems with balance and problems with hearing. These problems may be permanent. If used during pregnancy it can cause harm to the baby. It appears to be safe for use during breastfeeding. Gentamicin is a type of aminoglycoside. It works by stopping the bacteria from making protein, which typically kills the bacteria.

Gentamicin is also used in combination with other antibiotics to treat infections caused by gram positive organisms such as Staphylococcus aureus and certain species of streptococci. Additionally, gentamicin is used in combination with a penicillin antibiotic to treat endocarditis (infection of the heart).

Gentamycin forms part of the aminoglycoside group of antibiotics. It kills bacteria as a result of abnormal protein production in the bacterial cell (that is, it cannot produce any of its proteins correctly) and also as a result of damage to the bacterial cell membrane.

Gentamicin injection is used to treat certain serious infections that are caused by bacteria such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract.

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References:

https://en.wikipedia.org/wiki/Gentamicin

https://www.ncbi.nlm.nih.gov/m/pubmed/860719

https://www.ncbi.nlm.nih.gov/pubmed/4992660

 

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